About this study

This update provides information such as a study summary, eligibility criteria, and a list of participating center locations. If you are interested in participating in this study or you have more questions, please contact the center nearest to you.

Summary:

A total of 1,300 subjects with CSS, GCA, MPA, PAN, TAK, and WG will be enrolled in this study. Study subjects will only be seen once for this research study.

For this visit, you will be asked to:

• Discuss your medical history and disease
• Give blood (approximately 1 tablespoon) for DNA collection

Background

The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide researchers in vasculitis with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

Target Enrollment:

To be eligible to participate, you must:

Be an individual with a confirmed diagnosis of one of the following:

• Churg-Strauss syndrome
• Giant Cell Arteritis
• Microscopic Polyangiitis
• polyarteritis nodosa
• Takayasu’s arteritis
• Wegener’s granulomatosis

You are not eligible to participate if:

• You are unwilling to provide blood for DNA collection
• Are enrolled in another VCRC protocol (because we will already have collected your DNA)

How to Participate:

Please do not respond to this e-mail. In order to participate in a study, you must personally contact any of the participating institutions listed below by phone or e-mail.

Please contact the participating institution that is closest to your location.

[column col=”1/2″]Boston University School of Medicine (VCRC)
Boston, Massachusetts
Principal Investigator: Paul Monach
Contact Person: Daniel Finkel
Office: 617-414-2509
Email: [email protected][/column]
[column col=”1/2″]Cedars-Sinai Medical Center (VCRC)
Los Angeles, California
Principal Investigator: Michael Weisman, M.D.
Contact Person: Denise Salinas
Office: 310-360-9197
Email: [email protected][/column]

[column col=”1/2″]Cleveland Clinic Foundation (VCRC)
Cleveland, Ohio
Principal Investigator: Carol Langford, MD, MHS
Contact Person: Katie Gartner
Office: 216-445-1397
Email: [email protected][/column]

[column col=”1/2″]Hospital for Special Surgery (VCRC)
New York, New York
Principal Investigator: Robert Spiera, MD
Contact Person: Uzunma Udeh
Office: 212-774-2123
Email: [email protected][/column]

[column col=”1/2″]Mayo Clinic (VCRC)
Rochester, Minnesota
Principal Investigator: Ulrich Specks, MD
Contact Person: Sara Biorn
Office: 507-284-4862
Email: [email protected][/column]

[column col=”1/2″]Mount Sinai Hospital, Toronto (VCRC)
Toronto, Ontario Canada
Principal Investigator: Simon Carette, MD
Contact Person: Julia Farquharson
Office: 416-586-8616
Email: [email protected][/column]

[column col=”1/2″]St. Joseph’s Healthcare Hamilton (VCRC)
Hamilton, Ontario Canada
Principal Investigator: Nader Khalidi, MD
Contact Person: Sandra Messier, RCT
Office: 905-522-1155 x 35873
Email: [email protected][/column]

[column col=”1/2″]University of California at San Francisco (VCRC)
San Francisco, California
Principal Investigator: Sharon Chung, MD
Contact Person: Ruby Harrison
Office: 415-514-3502
Email: [email protected][/column]

[column col=”1/2″]University of Pennsylvania (VCRC)
Philadelphia, Pennsylvania
Principal Investigator: Peter Merkel, MD, MPH
Contact Person: Alexandra Giardino
Office: 215-614-4407
Email: [email protected][/column]

[column col=”1/2″]University of Pittsburgh (VCRC)
Pittsburgh, Pennsylvania
Principal Investigator: Larry Moreland, MD
Contact Person: Dawn McBride, RN, BA
Office: 412-586-3545
Email: [email protected][/column]

[column col=”1/2″]University of Utah (VCRC)
Salt Lake City, Utah
Principal Investigator: Curry Koening, MD, MS
Contact Person: Julieanne Nielsen, BS
Office: 801-585-0798
Email: [email protected][/column]