here are multiple genes/gene variants involved in GPA
There are multiple genes/gene variants involved in GPA and for certain these are also present in healthy people – one has to have the “right” combination of genes as well as some environmental trigger to get the disease.
Dr. Katherine Siminovitch
(From research funded by VFC, VF, the Erna Baird Memorial Grant & many others,
including DNA samples donated from thousands of GPA patients)